A Clinical Study In The Treatment And Management Of Chronic Fissure In Ano

Abstract

In the course of standard clinical practice, anal fissures are often observed. Surgical closure of anal fissures has long been the standard of care. More cautious methods of therapy have emerged as a consequence of advances in pharmacological knowledge of the internal anal sphincter. Topical 2% Diltiazem gel is compared in this research for its symptomatic alleviation, healing potential, and adverse effects.
Individuals who have symptoms of ano-fissure for a duration exceeding six weeks will be classified as having chronic ano-fissure and will be included in a randomized trial for comparison purposes.
Our research found that out of 100 patients, 76 (76.0%) were treated conservatively with local application diltiazem gel and had a full recovery from their fissure. Among these patients, 74 (97.4%) reported no adverse effects and just 2 (92.6%) reported experiencing them. After undergoing lateral sphincterotomy, 24 patients (24.0%) were able to achieve a full recovery.
When dealing with chronic fissure in the nose, topical diltiazem should be thought of as the first line of therapy. Only individuals who have had a recurrence after previous pharmaceutical therapy has failed should undergo an internal sphincterotomy.